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Brand name: tizanidine
Generic name: zanaflex, Tizanidine, Sirdalud, pain, muscle relaxer, muscle relaxant
tizanidine description:

In a study of 30 healthy volunteers administered a single 4 mg dose of tizanidine, mean peak plasma concentration (Cmax) of tizanidine was 3. According to the manufacturer, approximately 5% of patients treated with tizanidine in clinical studies had elevations in serum transaminases greater than 3 times the upper limit of normal (or 2 times if baseline levels were elevated), compared to 0. Tizanidine to metabolite ratios in plasma and urine were 2 to 10 times higher in the contraceptive users than in control subjects, and the excretion of unchanged tizanidine into urine was on average 3. Therapy with tizanidine should be administered cautiously in patients with or predisposed to hypotension. Therapy with tizanidine should be administered cautiously in patients with a history of psychiatric disorders.

tizanidine information at Drugs.com

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